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Posmatrani su : naj eae upotrebljavani lekovi koji deluju na nervni sistem (anksiolitici, sedativi, antidepresivi, antipsihotici) ostali lekovi koji mogu izmeniti psihofizi ke sposobnosti (analgetici, antihistaminici, antihipertenzivi, antidijabetici i hinolonski antibiotici) Potroanja je posmatrana na osnovu dva pokazatelja: broj utroaenih originalnih pakovanja godianje DDD/1000 stanovnika /danK    = F " ; u "  4 G qC+CCC  C CCCC C $C$(C(,C,0C04C48C8)Bhnjȫ;h<_$r{)=f0gl2W]`#xL3)Yrh,;H '&CiPK!1_a _rels/.relsj0 ѽqCNo^K [ILcX&m߾0XFo;>0xM e`|X}đ I`߽N4aG2$RKIZ)4(M9`ctB{m:f@`3n|O,ܗr޾jxR0T ,0@}WBLǬ5vPK!Ls`#drs/shapexml.xml]mo8 ~_]^mtXs݀`Plj>Y;oMҥ7ٖE>DOPڇmqᄮ'ۛ ۊ.COW1jő7RQRX!kPLD\(E_WJmv^-xk' nz>s(].]Io02P7tVlZO%$|S _PUj'rhUFq<_eM)Xk2ݪ]}dp8էj=7pZ|,_M,@Fq-+ijT-ju>B4(mdИ ܶ/"nۗFAxeP"H ڶUQp_S]я,Xݎc2pnG,{ i\,M3CXՓI4m2ag}&myQol<V hi'Y $1ˇlN-muŵ| =}w Xt22bpK1cc 9zdH3` K\lYIQxF^P͖xʥWIǗcЃ<ٽOSć HVȰA 2l/(fBrb60eR5,[Kzs܀K 3aG'F扖4֜k*i,Bmg.F01/͌LN4F ѶmNJ0L2Q2LIe;pWGIBRuR ^1X^ћ$|-LSlwVgF;i.rjo6cJWL~}m$bfX9x)Hcs6͖eXjYkIWmșn68Y.[sx«vq˫0Wra`gM[ت:-eǝn>GpGH2Zc 6m%5|eV|Ų,]4|=+Uwڡr8I &"qY"|_/[XT_"f>dI d!TaT+M4.'ttkzu"Z,9mP69`w] ˭O4#JR}PK!&!drs/_rels/shapexml.xml.relsAj0EA>E(Ų7mH0HcY I-#&@?=*~)eXA״ u0{ "dk`RQq}gZQ^\̢R8+XJ_Rf܄H\9$ʈm2=3`xa(H@\X<;MMa1a.M7mC"D!؜s_֤O%q Ca7Ir6:>h驦=)};eut߷+uW@Clx+Q/R@f)CqrܠD(EPK !-drs/media/image1.pngPNG  IHDRD٢PLTE)1)ZkZZck)k)R)ޔ)kZ)ZkΜJ)Μk)kkJkRޔJZZJΜJΜJJJZkZkﭜޭJcZJB)cc)Z:ckZJZ)JcBZ:BJZJZ:c޵)޵BތkkZ)ZB)RέޭkkkZZkZkZkޭZ)Z))Z)ZZ)ޭZ)ckk)k)kk)kk))))kk)kZJZέk)Z)J)kZkZkތZ)Z)ZέZ)ތZckJkk)έ)BJZBRΌJJZZJZJޭZZ)ZZZޭZ)BJkJJΜkJJ)JJZJZΌJZJJZJZJތZZZΌZތZBJΜJJJΌkZkZJJRkZkZk)kZ))!)ZJZJZkZ)JZ)1)c)OW)tRNSS%bKGDH cmPPJCmp0712Hs}IDATHKAn0E- &)=,]4I')r^#'&. 0HvByIlJ'cx)ƨ̥!uQvc>2ޣ$a$$dyOԂd%ǧ<(`S)q8?IENDB`PK-!R=% [Content_Types].xmlPK-!1_a ;_rels/.relsPK-!Ls`#6drs/shapexml.xmlPK-!&! drs/_rels/shapexml.xml.relsPK-!  drs/downrev.xmlPK- !- drs/media/image1.pngPK00 ___PPT9 Od 2006-2015. godine rashodi za lekove i medicinska sredstva u Srbiji su inili 1/5 -1/6 ukupnih troakova zdravstvene zaatite 1/8 ukupnih troakova za lekove- lekovi za nervni sistem Grafikon 1. 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Kao i kod nas, u veini evropskih zemalja (Skandinavija, Slovenija, Holandija) - porast upotrebe antidepresiva (vei od 10%) - porast upotrebe hipnotika i sedativa U veini zemalja - porast upotrebe sistemskih antihistaminika (u naaoj zemlji - blagi pad)f  ?   B  > ) CCCC.C C CC CC C  C  $C$$C$(C(,C,0C0 4C4"8C8Bhnjȫ;h<_$r{)=f0gl2W]`#xL3)Yrh,;H '&CiPK!1_a _rels/.relsj0 ѽqCNo^K [ILcX&m߾0XFo;>0xM e`|X}đ I`߽N4aG2$RKIZ)4(M9`ctB{m:f@`3n|O,ܗr޾jxR0T ,0@}WBLǬ5vPK!`|Cdrs/shapexml.xml\N8_iiZ:#`H(\9K3$Nv {g;M`Xffe Z'>NwOpB&HRq?.(D²BrEa9T%`eHgZVK33(@ߴ98WRrŅf7ʳV'zRfRi7cI$-%i!4qb>+KҥzШU{ Wd05(~SܠeYZp'i9v;w`rFΌ S/kGlXLﷃh݂A yؐ5t=CḵVHnߐ%!($d 5mo:8=j"3&b\5z<82,鑘!4s)җL419/&3VrKnFJViHDf{EbY7 N LBwz.H HEk ނeW>dFH^aĉ) W2c v3D8ygFCUXf0:ՄW)NtڐKޤڎKL^έjr40oK>cB0'A/{Eo ֳI1̢$KKUZ;~ӘZUB(o!,-P}ƦR7=ܢXYj~Y|5xt#N<=5Yя Ŏ%V|l-lG񫷳d}W}'m7 MfD{>ro5 VV[~S"-ޝzwj^4K3׈_ _ ~([-(y}dO!gMUPK!&!drs/_rels/shapexml.xml.relsAj0EA>E(Ų7mH0HcY I-#&@?=*~)eXA״ u0{ "dk`RQq}gZQ^\̢R8+XJ_Rf܄H\9$ʈm2=3`xa(H@\X<;Mvc>2ޣ$a$$dyOԂd%ǧ<(`S)q8?IENDB`PK-!R=% [Content_Types].xmlPK-!1_a ;_rels/.relsPK-!`|C6drs/shapexml.xmlPK-!&!drs/_rels/shapexml.xml.relsPK-!vdrs/downrev.xmlPK- !- drs/media/image1.pngPK"0P* ___PPT9 >Navedena odstupanja u rezultatima se mogu objasniti: postojanjem razli itih protokola propisivanja lekova sociodemografskim i ekonomskim razlikama 5  7   +      C!C C C  C"C CC C C C $C$(C(,C,0C04C4 ! $ "$  $$$$$  H JI8]TextBox 4"êPK![Content_Types].xmlJ0*miG]`Hm6 Xwt?. g#Wi3E).+7 >ON ޑ1ˋz "+R RhB.} /<^ITխ%rHK4uK~I0xM e`|X}đ I`߽N4aG2$RKIZ)4(M9`ctB{m:f@`3n|O,ܗr޾jxR0T ,0@}WBLǬ5vPK!.E+drs/shapexml.xmlZQo8~?KhcMWm%NVhpq"p_c; ڇte6N\Ū]t5uT a> s 3W59>VH->GfSzjVx|֔Ӽ9G9V%.T CBǓbY,ve<2E'HX#e0(Iy9.wqxwd4h##Ⱥl@vdVy\+6cƇx`CTg粍ر63ս-b|Ο=D < Fo;|z1Rֳr^ n)x__݃ Yc(jy~J#iS'2c LJC%el 9s?a1tRBhnjȫ;h<_$r{)=f0gl2W]`#xL3)Yrh,;H '&CiPK!1_a _rels/.relsj0 ѽqCNo^K [ILcX&m߾0XFo;>0xM e`|X}đ I`߽N4aG2$RKIZ)4(M9`ctB{m:f@`3n|O,ܗr޾jxR0T ,0@}WBLǬ5vPK! 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W"C6drs/shapexml.xmlPK-!&!d drs/_rels/shapexml.xml.relsPK-!sY drs/downrev.xmlPK- !-b drs/media/image1.pngPKP ` ___PPT9 BJ Upotreba benzodijazepina = 2,3 puta vei rizik od saobraajnih nezgoda sa smrtnim ishodom. Drugi lekovi : opioidni analgetici-1,68; antidepresivi-1,35; antiastmatici-1,3 puta vei rizik. Rezultati studija drugih grupa lekova (npr. opioidi, antidepresivi i dr.) - opre ni ili nedovoljno informativni za jasno zaklju ivanje Problem: nemogunost utvrivanja povezanosti upotrebe leka sa nastankom saobraajne nezgode. l [  `    ^  Ccc c c cc c c $c$(c(Q,c,0c04C48C8 Bhnjȫ;h<_$r{)=f0gl2W]`#xL3)Yrh,;H '&CiPK!1_a _rels/.relsj0 ѽqCNo^K [ILcX&m߾0XFo;>0xM e`|X}đ I`߽N4aG2$RKIZ)4(M9`ctB{m:f@`3n|O,ܗr޾jxR0T ,0@}WBLǬ5vPK!;U fdrs/shapexml.xml]mo6>`!K46lˆScAItF4NIQ$7KQ)sϑ<iBnq}g#Y+ry~t(hq{LzN}>97S*Z2?qf" NU+L2InRso&XPf,HI#aL ,K"&Hk7{)dhײ}J"ACQ2Dx2u Z&K.w2_ u.Ԧ পDҔS4k N~wPO:: YP$nׅL-S2|gYtoq}~ @)Ly仠P9#'.} kʜxDcz ,рCx)*8ӥҜN˒ .Rn>g͙I@oFRiiͩDMK`5|R*Fw|=GTBr{G.M-bKL  P6FGL\>*5n@\^D-3ʯ79=]:2ǡ"7TcPgl$L ϨR|մ D\.LE]<u)((bx$EV k*Xb, ֪<[l%UbJsD`Ak/kML#L(PSH OZ'ǜjIbbȲ GPPm,cs vVpF=#ZgmmzuAZ Jl<+m 3>􁐥gh68ɯֳ$;h创D.P[_(`-HH4tx4ƯD8K8+o[Z ]\ q{ ?ÂeOl+X#Aڢ}~/ +V8,V;?AO~ ^OA5Z4.SЍ1qڡtc uXW>M97IF65WC݅y㍾dA&8zh:j}D ]Q..#oi]F.c]4T *%?pl˯F7A;wfW3e˽6l֮aPQqBi$)w5#$ʳ;OmWxOhM(e붗y5ʌ]$Eu,EWn>Ā=Х5,w M+`n߱jjrWݚٽFx2C 5mؤ"F.͞tplhw7*:.8\5u^8SnkjGyPK!&!drs/_rels/shapexml.xml.relsAj0EA>E(Ų7mH0HcY I-#&@?=*~)eXA״ u0{ "dk`RQq}gZQ^\̢R8+XJ_Rf܄H\9$ʈm2=3`xa(H@\X<;Mvc>2ޣ$a$$dyOԂd%ǧ<(`S)q8?IENDB`PK-!R=% [Content_Types].xmlPK-!1_a ;_rels/.relsPK-!;U f6drs/shapexml.xmlPK-!&!n drs/_rels/shapexml.xml.relsPK-!c drs/downrev.xmlPK- !-k drs/media/image1.pngPK `` ___PPT9|t Nedostupnost adekvatnih podataka- nema mogunosti procene povezanosti upotrebe lekova sa veim rizikom od nastanka saobraajnih nezgoda. Upotreba psihoaktivnih supstanci kao poseban uticajni faktor u okviru pokazatelja bezbednosti saobraaja evidentira se od 2016. godine. Najnovije istra~ivanje ABS o stavovima u esnika u saobraaju : vo~nja pod uticajem lekova i droga prepoznata je od strane samih u esnika u saobraaju kao jedan od faktora rizika za nastanak sabraajnih nezgoda. *    ?  C C C. 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